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Patient Inquiry:Aczone is a new topical drug approved dec 2008. I was wondering if Dr. Ali could look into it and prescribe it to me. People with cystic acne have seen great results. Dermatologists have been prescribing it to their patients already. Please let me know.http:www.acne.orgmessageboardBefore-and-Pics-2-weeks-t222896Dr. Dima Response:Dapsone is not a new drug. It's been around a long time but Alex McGough Jersey , when it's given a new name or indication, it gets press coverage and, for people looking for "the ultimate acne answer," it becomes the new best thing. Orally it is primarily indicated for leprosy, lupus and HIV opportunistic infections such as pneumocystis pneumonia and toxoplasmosis but must be closely monitored as it can have a deleterious effect on red blood cells. Topically it was originally used for rosacea and Rasheem Green Jersey , although the mechanism of action remains unknown, it may work for some types of inflammatory acne but is unlikely to work for cystic acne. Doctors should screen patients potentially predisposed to G6PD enzyme deficiency (glucose 6-phosphate dehydrogenase) as use of dapsone can cause a blood disorder called hemolytic anemia (more likely if taken orally). I would caution against long term (over 12 weeks) topical use on extensive body surface area to avoid systemic absorption (many people have acne on the face, back, shoulders and chest). The gel form of dapsone was made by Canadian company QLT Inc., and sold as Aczone Gel Michael Dickson Jersey , 5%.This past summer, Allergan announced its purchase of Aczone 5% from the Canadian company. Allergan paid about $150 million for all assets related to Aczone with estimated revenues in excess of $75 million per year. Patients can actually get a free sample sent to them from Allergan by filling out a form on-line. If they want to give it a try, I would caution use of anything that contains benzoyl peroxide (even as a face wash) as your skin may turn orange. In my opinion, as with many "acne miracle meds," it's really just a lot of good marketing and with a name like Allergan now backing it up Will Dissly Jersey , it will likely get more press coverage than it's worth. For the topical treatment of acne, nothing comes close to the tried and true tretinoin.
LONDON, June 30 (Xinhua) -- Defending champion Andy Murray advanced to the quarterfinals after defeating Kevin Anderson on Monday and will face rising star Grigor Dimitrov of Bulgaria in first real test at Wimbledon.


Finishing under a closed Centre Court roof, the Scot swept past Anderson from South Africa 6-4, 6-3 Rashaad Penny Jersey , 7-6 (7-6) to make it into last eight for the seventh year in a row.


Murray has a 3-1 winloss over Dimitrov heading into their dual. It was the Bulgarian who won their most recent encounter, on hard court in the Acapulco semifinals earlier this year.


"Now he's starting to come into his prime," said Murray of Dimitrov. "He's won a lot of matches this year. He's a tough player. It will be a hard match for me. It's a big opportunity for him, as well, playing on the Centre Court at Wimbledon for the first time. It's a great opportunity for him. Hopefully we can play a good match."


The third-seeded Murray is yet to drop a set in four matches at the All England Club.


Against Anderson Wholesale Seattle Seahawks Jerseys , who was playing on Centre Court for the first time, Murray raced to a 6-4, 3-0 double break lead before the rain came, forcing the players back to the locker room for 27 minutes while the roof was closed.


At the resumption, Anderson came out more aggressive and made life difficult for Murray Wholesale Seahawks Jerseys , who was forced to save a set point in the tie-break before sealing victory in two hours and 32 minutes.


"When it was outdoors, I played well and was in a good position," Murray said. "When we came back indoors, he started to strike the ball better, he was serving better and I was dropping the ball shorter than I had done. I had more running to do at the end and I got a bit tentative. It was a good win for me; he made it tough."


The 27-year-old Murray ended Britain's 77-year wait for a homegrown male Wimbledon champion last year as he beat Novak Djokovic in the final to lift his second Grand Slam trophy.


Serbia's top seed Djokovic also had an easy time of it as he defeated Jo-Wilfried Tsonga of France for the 11th match in a row on the same matchday. The Serbian master needed just one hour and 51 minutes minutes to advance at 6-3 Cheap Seattle Seahawks Jerseys , 6-4, 7-6(7-5).


Djokovic has not lost to Tsonga since the 2010 Australian Open quarterfinals and improved to a 13-5 winloss record against the Frenchman.


"Tsonga is a top player," said Djokovic. "I was very happy with my consistency today, mental consistency, and variety in my game. I played very well from back of the court."


For a place in the Wimbledon last four Cheap Seahawks Jerseys , Djokovic will challenge Marin Cilic, whom he has not lost to in nine previous meetings.

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